SOME POSSIBLE CAUSES OF CONGENITAL HEART MALFORMATION

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Some possible causes of congenital heart malformation.

Certain conditions found in human congenital heart disease are probably genetic in origin (Cockayne, 1938; Polani and Campbell, 1955), but sometimes they may be correlated with an environmental factor, namely the infection of the mother with rubella during early pregnancy. Thus there appears to be no single cause of congenital heart abnormality; sometimes genetic causes and sometimes environmen...

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The familial incidence of congenital malformation of the heart.

It is generally believed that the incidence of congenital malformation of the heart is raised in relatives of affected individuals. The evidence in support of this view consists mainly of isolated records of families with more than one affected member (Courter et al., 1948, refer to 63 reported cases), but a few examples have been noted in the course of investigations of large series of patient...

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ژورنال

عنوان ژورنال: Heart

سال: 1959

ISSN: 1355-6037

DOI: 10.1136/hrt.21.1.51